Established in 1998 by a team of scientists from the Max-Planck-Institute of Molecular Physiology (Dortmund), Jena Bioscience utilises more than 25 years of academic know-how to develop innovative reagents for clients from both research and industry in 100+ countries. To date, Jena Bioscience still remains an owner-operated business.

In the chemistry division, they have hundreds of natural and modified nucleotides in stock. In addition, with their pre-made building blocks and in-house expertise they manufacture even the most exotic nucleotide analog from mg to kg scale.

In the field of recombinant protein production, Jena Bioscience has developed its proprietary LEXSY (Leishmania Expression System) technology. It is based on an S1-classified unicellular organism that combines easy handling with a eukaryotic protein folding and modification machinery.

For the crystallization of biological macromolecules – which is often the bottleneck in determining the 3D-structure of proteins – they offer specialised reagents for protein stabilisation, crystal screening, crystal optimisation, and phasing that can reduce the time necessary to obtain a high resolution protein structure.


Product Categories

Product Lists

Jena Bioscience’s products include nucleosides, nucleotides and their non-natural analogs, recombinant proteins & protein production systems, reagents for Click Chemistry, for crystallization of biological macromolecules and tailor-made solutions for molecular biology.

In our chemistry division, we have hundreds of natural and modified nucleotides in stock. In addition, with our pre-made building blocks and in-house expertise we manufacture even the most exotic nucleotide analog from mg to kg scale.

In the field of recombinant protein production, Jena Bioscience has developed its proprietary LEXSY technology. LEXSY (Leishmania Expression System) is based on a S1-classified unicellular organism that combines easy handling with a eukaryotic protein folding and modification machinery including mammalian-like glycosylation. LEXSY is primarily used for the expression of proteins that are expressed at low yields or are inactive in the established systems, and expression levels of up to 500 mg/L of culture were achieved.

For the crystallization of biological macromolecules – which is the bottleneck in determining the 3D-structure of most proteins – we offer specialized reagents for protein stabilization, crystal screening, crystal optimization and phasing that can reduce the time for obtaining a high resolution protein structure from several years to a few days.

Our reagents are complemented with a large selection of molecular biology kits for PCR, mutagenesis, cloning and alike as well with innovative reagents for the functionalization and labeling (fluorophores, haptens) of biomolecules with focus on Click Chemistry approaches.


Increase synthetic mRNA functionality with nucleoside base modifications

Contact UsView All Products 5’-capping and nucleoside base modifications significantly increase translation efficiency while reducing immunogenicity of synthetic mRNA (Fig. Read More...

Efficient RNA Labeling with abberior® STAR dyes

Contact UsView All Products Abberior® STAR 580 and STAR RED dyes are hydrophilic fluorescent dyes with remarkable photostability that give Read More...

Tight budget, tight schedule? Do it with Direct PCR!

Contact UsView All Products Direct qPCR and RT-qPCR Kits from Jena Bioscience save you time and money – just add Read More...

Crystallization of LEXSY-produced Helminth proteins

Contact Us View All Products LEXSY (Leishmania Expression System) is a eukaryotic protein expression platform based on the S1-classified protozoan L. tarentolae. It combines Read More...

Choose your ideal PCR Polymerase

Contact UsView All Products Jena Bioscience offers a range of high performance DNA polymerases. We've got something for you whether you're Read More...

New: Nuclease Detection – As simple as this!

Contact UsView All Products Nucleases (e.g. DNases & RNases) are enzymes facilitating the cleavage of phosphodiester bonds in nucleic acids (RNA, Read More...

Give it a hot start – avoid unspecific PCR products!

Contact Us View All Products Standard thermostable polymerases (e.g. Taq) show an optimal performance around 70°C. Yet, moderate enzymatic activity Read More...

mRNA quality control: Easy detection of dsRNA impurities

Contact UsView All Products Double-stranded RNA (dsRNA) is a major impurity of therapeutic mRNA produced by in vitro transcription. Impurity levels of Read More...

LAMP just got even faster!

Contact UsView All Products LAMP – loop-mediated DNA amplification at constant temperature (Isothermal Amplification) offers key advantages over conventional PCR. Not Read More...

N1-Methylpseudouridine: Increase mRNA vaccine effectiveness

Contact UsView All Products An effective mRNA vaccine is characterized by high protein (= antigen) expression and low innate immunogenicity. Read More...

Click Chemistry - Jena Bioscience

Click Chemistry

Click Chemistry[1] describes pairs of functional groups that rapidly and selectively react (“click”) with each other under mild, aqueous conditions. The Read More...

Click Reagents by Chemistry

Contact Us Click Chemistry[1] describes pairs of functional groups that rapidly and selectively react (“click”) with each other under mild, aqueous Read More...

Click Reagents by Application

Contact Us Click Chemistry[1] describes pairs of functional groups that rapidly and selectively react ("click") with each other under mild, aqueous Read More...

RNA Technologies

Contact Us Ribonucleic acids (RNAs) are essential for transfer of genetic information and cell regulation. About 1-2% of the transcribed genome (transcriptome) Read More...

Epigenetics

Contact Us DNA (De)MethylationNucleotides & Nucleosides Products & Ordering 5-Methyl-dCTP NU-1125 mdCTP, 5-mdCTP 5-Hydroxymethyl-dCTP NU-932 hmdCTP, 5hmdCTP 5-Aza-dCTP NU-1118  5-Hydroxymethyl-dC Read More...

Protein Labeling

Contact Us The attachment of a reporter group (label) is often required for the detection and biochemical/cellular characterization of proteins Read More...

RNA/cRNA Labeling

Contact Us Fluorophores and haptens, are the most commonly used labels for the generation of non-radioactive RNA/cRNA probes. They are enzymatically introduced Read More...

DNA/cDNA Labeling

Fluorophores and haptens, are the most commonly used labels for the generation of non-radioactive DNA/cDNA probes. They are enzymatically introduced into DNA/cDNA Read More...

Probes & Epigenetics

Reactive Components Reactive Fluorescent, Hapten-modified and bifunctional reagents for labeling and crosslinking of biomolecules such as DNA, RNA and proteins DNA/cDNA Labeling Read More...

Cell Labeling

Contact Us Fluorescent reporter and Protein & Nucleotide internalization reagents The visualization of cells and cellular structures as well as Read More...