monoclonal or polyclonal

Which antibody to choose, monoclonal or polyclonal ?

Antibodies are proteins found in plasma and extracellular fluids and are the first response to infection as well as the Read More…

Exosomes Explained

How to use Exosomes

Exosomes Tools, from isolation to engineering Exosomes – extracellular vesicles (EVs) 30 – 200 nm in size were once thought Read More…

Technical Tips

Technical Tips for Secondary Antibodies

Simultaneous detection of more than one antigen depends on: Secondary antibodies that do not; recognise one another recognise other primary Read More…

Liposome Prep

Liposome Preparation Made Simple

Introduction – what is a liposome? Liposomes are spherical vesicles made up of one or more phospholipid bilayers known as Read More…

Full Spectrum Multiple Labelling

Calcium acts as a universal second messenger in a variety of cells. Numerous functions of all types of cells are Read More…

Calcium Dyes Past, Present and Future

A History of Calcium Indicators in Life Science

Introduction to calcium dyes Calcium ions (Ca2+) play a crucial physiological role in the body: signalling, blood clotting, in cellular Read More…

Notch Signaling and CNS

Notch signaling is initiated and activated by direct cell-cell interactions that facilitate binding between the four Notch receptor isoforms (Notch1-4) Read More…

Agarose

Agarose is a purified hydrogel isolated from red algae; it is the main component of agar. Structurally, agarose is a Read More…

How Lentivirus Delivery Works

The pseudoviral particles can infect target cells and express genes, shRNAs, microRNAs and reporter molecules but cannot replicate within the Read More…

Exo-Fect™ Exosome Transfection

Exo-Fect is a novel nucleic acid transfer agent that enables the transfection of nucleic acids directly into isolated exosomes. The Read More…

PinPoint Targeted Integration System

The PinPoint Targeted Integration system allows users to easily and efficiently create isogenic stable cell lines in mammalian and other Read More…

Minicircle DNA Vector Technology

The Minicircle advantage Minicircles are episomal DNA vectors that are produced as circular expression cassettes devoid of any bacterial plasmid Read More...