Secretory IgA EIA Kit Research
Catalogue Number: 1-1602-SAL
| Manufacturer: | Salimetrics LLC |
| Type: | Human ELISA Kit |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 4°C |
| Unit(s): | 96 Tests |
| Range: | 2.50 µg/mL – 600 µg/mL |
| Sensitivity: | 2.5 µg/mL |
| Sample type: | Saliva |
| Sample size: | 25 µL |
| Application: | ELISA |
Description
Description: Salimetrics salivary assay kits are expertly designed, developed and validated to ensure accuracy in saliva and proven to deliver precision results for saliva biomarkers.The Salimetrics Salivary IgA (SIgA, Secretory Immunoglobulin-A) Enzyme Immunoassay Kit was specifically designed to standardize the detection of secretory IgA in saliva samples for research and biomedical laboratories. Using a small sample volume, this assay kit has an extended range which spans the expected secretory IgA levels found in human saliva. The average inter- and intra-assay precision coefficients of variation are low with no deleterious matrix effects often found in saliva which are characterized through dilution- and spike-recovery validation procedures. This secretory IgA assay kit has also been formatted to minimize cross reactivity for related cytokines. Secretory immunoglobulin A (SIgA) is often characterized as a component of the immune systems “first-line of defense” against pathogenic microorganisms, viruses, and bacteria. A lower concentration of SIgA in saliva has been conceptualized as a risk factor for upper respiratory infection in children and the elderly. Also, individual differences in SIgA levels in response to infection have been identified as potential risk factors. Lower levels of SIgA are associated with increased risk for periodontal disease and caries. Several studies link stress and emotionality with levels of SIgA . SIgA has a parabolic relationship with age. No gender differences in SIgA levels have been reported. SIgA in saliva is not directly related to serum levels of SIgA. This literature recommends that variability in salivary flow rate should be taken into account when estimating saliva levels of SIgA and making comparisons between individuals. The present enzyme immunoassay protocol represents a significant advance over the traditional SIgA measurement approach by employing single radial immunodiffusion (SRID).
1-1602 Protocol
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