Monoclonal Antibody to SARS-CoV-2 nucleocapsid (Clone: ABM4H11.1C12)

Catalogue Number: 10-10035-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM4H11.1C12
Isotype: IgG2b, kappa
Immunogen: Full length recombinant SARS-CoV-2 nucleocapsid Protein was used as the immunogen for this antibody.
Application: ELISA, WB

Description

Description: The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.

Additional Text

Gene Name

N

Purification

Protein G purified

Antibody Clonality

Monoclonal

Application Notes

Recommended dilutions: WB: 0.1-1 µg/ml, ELISA: 1 µg/ml. However, this need to be optimized based on the research applications.

Gene ID

43740575

Uniprot ID

P0DTC9

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.