Monoclonal Antibody to TLR6 (Clone: ABM1B50)
Catalogue Number: 10-3002-ABO
10-3002 Image
10-3002 Image
10-3002 Image
Fig-1: Intracellular flow analysis of TLR6 in THP-1 cells using 0.5 µg/10^6 cells of TLR6 antibody (Clone: ABM1B50). Green represents isotype control; red represents anti-TLR6 antibody. Goat anti-Mouse PE conjugate was used as secondary antibody.
10-3002 Image
Fig-2: Western blot analysis of TLR6. Anti- TLR6 antibody (Clone: ABM1B50) was used at 2 µg/ml on Jurkat lysate.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | TLR6 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Mouse |
| Clone: | ABM1B50 |
| Isotype: | IgG1, kappa |
| Immunogen: | A partial length recombinant TLR6 protein (amino acids 280-512) was used as the immunogen for this antibody. |
| Application: | FACS, WB |
Description
Description: TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression.
Additional Text
Gene ID
10333
Gene Name
TLR6
Purification
Protein G purified
Uniprot ID
Q9Y2C9
Antibody Clonality
Monoclonal
Application Notes
Western blot analysis: 2-4 µg/ml; FACS analysis: 0.5-1 µg/10^6 cells
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
10-3002 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations