Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6)
Catalogue Number: 10-3005-ABO
10-3005 Image
10-3005 Image
10-3005 Image
Fig-2: Immunohistochemical analysis of TLR8 in small cell carcinoma of esophagus using TLR8 antibody (Clone: ABM15F6) at 5 µg/ml.
10-3005 Image
Fig-1: Intracellular flow analysis of hTLR8 in U937 using 2 µg/10^6 cells of hTLR8 antibody (Clone: ABM15F6). Green represents isotype control; red represents anti-hTLR8 antibody. Goat anti-mouse PE conjugate was used as secondary.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | TLR8||UNQ249/PRO286 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Mouse |
| Clone: | ABM15F6 |
| Isotype: | IgG1, kappa |
| Immunogen: | A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody. |
| Application: | FACS, IHC |
Description
Description: Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
Additional Text
Gene Name
TLR8
Gene ID
51311
Purification
Protein G purified
Uniprot ID
Q9NR97
Antibody Clonality
Monoclonal
Application Notes
Immunohistochemical analysis: 5 µg/ml;FACS analysis: 2 µg/10^6 cells
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
10-3005 Datasheet
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