Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6)

Catalogue Number: 10-3005-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:TLR8||UNQ249/PRO286
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM15F6
Isotype: IgG1, kappa
Immunogen: A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody.
Application: FACS, IHC

Description

Description: Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.

Additional Text

Gene Name

TLR8

Gene ID

51311

Purification

Protein G purified

Uniprot ID

Q9NR97

Antibody Clonality

Monoclonal

Application Notes

Immunohistochemical analysis: 5 µg/ml;FACS analysis: 2 µg/10^6 cells

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.