Monoclonal Antibody to TLR8/CD288 FITC Conjugated (Clone: ABM15F6)

Catalogue Number: 10-3005-F-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Conjugated
Alias:TLR8||UNQ249/PRO286
Shipping Condition:Blue Ice
Unit(s): 25 ug, 100 ug
Host name: Mouse
Clone: ABM15F6
Isotype: IgG1, kappa
Immunogen: A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody.
Application: FACS

Description

Description: Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.

Additional Text

Gene Name

TLR8

Gene ID

51311

Purification

Protein G purified

Uniprot ID

Q9NR97

Antibody Clonality

Monoclonal

Application Notes

FACS analysis: 0.5-1 µg/10^6 cells

Storage Note

Store the antibody at 4°C, stable for 6 months.