Monoclonal Antibody to TLR7 (Clone: ABM2C27)
Catalogue Number: 10-3015-ABO
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Fig-2: Intracellular flow analysis of TLR7 in PBMC (Lymphocyte) using 0.5 µg/10^6 cells of TLR7 antibody (Clone: ABM2C27). Green represents isotype control; red represents anti-TLR7 antibody. Goat anti-mouse PE conjugate was used as secondary.
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Fig-3:Immunohistochemical analysis of TLR7 in Renal Cell Carcinoma using TLR7 antibody (Clone: ABM2C27) at 5 µg/ml.
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Fig-4: Intracellular flow analysis of TLR7 in Raji cells using 0.5 µg/10^6 cells of TLR7 antibody (Clone: ABM2C27). Green represents isotype control; red represents anti-TLR7 antibody. Goat anti-mouse PE conjugate was used as secondary antibody.
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Fig-1 : Immunohistochemical analysis of TLR7 in human Kidney tissue using TLR7 antibody (Clone: ABM2C27) at 5 µg/ml.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | TLR7||UNQ248/PRO285 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Mouse |
| Clone: | ABM2C27 |
| Isotype: | IgG1, kappa |
| Immunogen: | A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody. |
| Application: | FACS, IHC |
Description
Description: TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells.
Additional Text
Gene Name
TLR7
Gene ID
51284
Purification
Protein G purified
Uniprot ID
Q9NYK1
Antibody Clonality
Monoclonal
Application Notes
FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
10-3015 Datasheet
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