Monoclonal Antibody to TLR7 (Clone: ABM2C27)

Catalogue Number: 10-3015-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:TLR7||UNQ248/PRO285
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM2C27
Isotype: IgG1, kappa
Immunogen: A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody.
Application: FACS, IHC

Description

Description: TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells.

Additional Text

Gene Name

TLR7

Gene ID

51284

Purification

Protein G purified

Uniprot ID

Q9NYK1

Antibody Clonality

Monoclonal

Application Notes

FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.