Monoclonal antibody to Mouse TLR4 CD284 (Clone: MTS510) FITC Conjugated

Catalogue Number: 10-3022-F-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD284
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Rat
Clone: MTS510
Isotype: IgG2a, kappa
Immunogen: This antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2
Application: FACS

Description

Description: TLR4 (Toll-like receptor-4) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. It primarily mediates cellular signaling induced by Gram negative bacteria. TLR4 is highly specific for LPS and it is associated with CD14, a co-receptor for LPS. The downstream signaling pathway of TLR4 leads to the activation of NF-kappaB through myeloid differentiation protein (MyD88) and IL-1 receptor-associated kinase in various cell types.

Additional Text

Gene Name

TLR4

Gene ID

21898

Purification

Protein G purified

Uniprot ID

Q9QUK6

Antibody Clonality

Monoclonal

Application Notes

FACS: 0.5-1 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months.