Monoclonal Antibody to TLR2 (Clone: ABM3A87)

Catalogue Number: 10-3026-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:TLR2||TIL4
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM3A87
Isotype: IgG1, kappa
Immunogen: A partial length recombinant TLR2 protein (amino acids 180-420) was used as the immunogen for this antibody.
Application: FACS, IF, WB, IHC

Description

Description: TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns). TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.

Additional Text

Gene Name

TLR2

Gene ID

7097

Purification

Protein G purified

Uniprot ID

O60603

Antibody Clonality

Monoclonal

Application Notes

Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.