Monoclonal Antibody to Ikk Gamma (Clone: ABM15D9)

Catalogue Number: 10-6017-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:IKBKG||FIP3||NEMO
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM15D9
Isotype: IgG1, kappa
Immunogen: A full length recombinant Ikk Gamma protein was used as the immunogen for this antibody.
Application: FACS, WB

Description

Description: IKK is a trimeric protein complex consisting of two catalytic subunits, IKKalpha and IKKbeta, and a regulatory subunit, IKKgamma. IKKgamma (also termed NEMO or IKBKG) regulates the kinase activity of IKKalpha/beta. IKKgamma plays a critical role in DNA damaged-induced NF-kappaB signaling in a role independent of its function in the IKK complex. While the biological importance of IKKgamma PTMs (Post-Translational Modifications) has been reported under a variety of stimuli, the detection of PTMs has numerous technical limitations. These limitations include both the transient nature of these modifications, as well as low overall abundance of modified IKKgamma inside the cell.

Additional Text

Gene Name

IKBKG

Gene ID

8517

Purification

Protein G purified

Uniprot ID

Q9Y6K9

Antibody Clonality

Monoclonal

Application Notes

Western blot analysis: 2-4 µg/ml, Flowcytometric analysis: 0.5-1 µg/10^6 cells

Storage Note

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.