Monoclonal Antibody to p105/p50 (Clone: ABM20H5)

Catalogue Number: 10-6021-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:NFKB1
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: ABM20H5
Isotype: IgG1, kappa
Immunogen: A partial length recombinant p50 protein (amino acids 1-200) was used as the immunogen for this antibody.
Application: WB

Description

Description: p50 (KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B) family of transcription factors plays important roles in various biological processes including apoptosis, stress response, immunity, and inflammation. Activation of p50 regulates the expression of inflammatory genes crucially involved in the pathogenesis of inflammatory diseases. It governs the expression of adhesion molecules that play a pivotal role in leukocyte-endothelium interactions. p50 activation plays an essential role in the activation of mesangial cells and macrophages through the transcriptional induction of inflammatory mediators of glomerular inflammation and injury.

Additional Text

Gene Name

NFKB1

Gene ID

4790

Purification

Protein G purified

Uniprot ID

P19838

Antibody Clonality

Monoclonal

Application Notes

Western blot analysis: 1-2 µg/ml

Storage Note

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.