Monoclonal Antibody to Mouse PD-1 (Clone: ABM5F42)

Catalogue Number: 10-7612-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Programmed cell death protein 1|| Protein PD-1|| CD279
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rat
Clone: ABM5F42
Isotype: IgG2b, kappa
Immunogen: partial length recombinant protein (a.a 07-211) of mPD-1 was used as the immunogen for this antibody.
Application: FACS

Description

Description: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Additional Text

Gene Name

PDCD1

Purification

Protein G purified

Uniprot ID

Q02242

Gene ID

18566

Antibody Clonality

Monoclonal

Application Notes

FACS: 0.5-1 µg/10^6

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.