Purified Anti-human CD2 Antibody *HIT11*
Catalogue Number: 10020000-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | HIT11 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | ELISA, FC, WB |
Description
Description: HIT11 is an anti-human monoclonal antibody that recognizes the CD2 antigen. CD2 (sometimes referred to as LFA-2) is a 45 kD single-pass type I membrane protein that is found on the surface of cells like T cells. CD2 has been thought to be involved with key biological processes such as cell-cell adhesion, especially heterotypic cell-cell adhesion. Also, in some organisms, it enhances myeloid dendritic cell activation, acts to positively regulate interferon-gamma secretion and is an enhancer of tumor necrosis factor production. CD2 is involved with key cellular pathways, for instance, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as LFA-3, CD59, CD58 and CD48. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography.
Additional Text
Antibody Clonality
Monoclonal
Storage Note
Refrigerated (2-8 °C); Minimize light exposure;|12 months
10020000 Protocol
SUPPORT
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DELIVERY
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