Purified Anti-human CD2 Antibody *RPA-2.10*
Catalogue Number: 10021000-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | RPA-2.10 |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, FC, WB |
Description
Description: RPA-2.10 is an anti-human monoclonal antibody that is specific for the CD2 antigen. CD2 (sometimes referred to as T11, Rosette receptor, Erythrocyte receptor or LFA-2) is a 45 kD single-pass type I membrane protein that is located on the surface of cells such as T cells, B cells and NK cells. In certain organisms, CD2 positively regulates interleukin-8 secretion, enhances myeloid dendritic cell activation and is an enhancer of interferon-gamma secretion. Also, it has been thought to be involved with important biological processes like cell-cell adhesion, specifically heterotypic cell-cell adhesion. CD2 is involved with key cellular pathways, in particular, the cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands like CD48, LFA-3 and CD58. CD2 is a moderately popular antibody target, with over 16000 publications in the last decade. CD2 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of costimulatory molecules and immunology. This antibody was purified through affinity chromatography.
Additional Text
Antibody Clonality
Monoclonal
Storage Note
Refrigerated (2-8 °C); Minimize light exposure;|12 months
10021000 Protocol
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