Purified Anti-human CD3 Antibody *UCHT1*
Catalogue Number: 10032000-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | UCHT1 |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, FC, WB |
Description
Description: The UCHT1 monoclonal antibody binds to human CD3e, a 20 kD member of the Ig superfamily commonly found on the surface of tregs, thymocytes, nkt cells and thymocytes (differentiation dependent)s. In many organisms, CD3 enhances interleukin-4 production, is an inhibitor of gene expression and negatively regulates smoothened signaling pathway. Also, it plays a role in essential cellular pathways, for instance, the cell surface receptor signaling pathway, T cell receptor signaling pathway and apoptotic signaling pathway. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands like TCR. CD3 is a very popular antibody target, with over 80000 publications in the last decade. CD3e is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography.
Additional Text
Antibody Clonality
Monoclonal
Storage Note
Refrigerated (2-8 °C); Minimize light exposure;|12 months
10032000 Protocol
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