Catalogue Number: 10082000-AAT
Manufacturer: | AAT Bioquest |
Shelf Life: | 12 months |
Type: | Monoclonal Primary Antibody - Unconjugated |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug |
Host name: | Mouse |
Clone: | OKT-8 |
Isotype: | IgG2a |
Immunogen: | |
Application: | ELISA, FC, WB |
Description: OKT-8 is an anti-human monoclonal antibody that forms an immune complex with the CD8a antigen. CD8a (alternatively called T8 or MAL) is a 32 - 34 kD transmembrane glycoprotein that is located on the surface of cells such as T cells. CD8 is a component of essential cellular pathways, namely, the transmembrane receptor protein tyrosine kinase signaling pathway and cell surface receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like Lck and MHCI. CD8 is a very popular antibody target, with over 120000 publications in the last decade. CD8a has a variety of applications in immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography.
Monoclonal
See Protocol|12 months