Purified Anti-human CD19 Antibody *SJ25C1*

Catalogue Number: 10191000-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: SJ25C1
Isotype:
Immunogen:
Application: ELISA, FC, WB

Description

Description: SJ25C1 is an anti-human monoclonal antibody that forms an immune complex with the CD19 antigen. CD19 (sometimes called T-cell surface antigen Leu-12 or B-lymphocyte surface antigen B4) is a 95 kD transmembrane glycoprotein that is located on the surface of cells such as stem cells, B cells and dendritic cells. CD19 is a member of key cellular pathways, in particular, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. Additionally, in many organisms, it upregulates release of sequestered calcium ion into cytosol, promotes protein kinase B signaling and is a promoter of phosphatidylinositol 3-kinase activity. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as CD225. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography.

Additional Text

Antibody Clonality

Monoclonal

Storage Note

Refrigerated (2-8 °C); Minimize light exposure;|12 months