Catalogue Number: 1091-INB
Manufacturer: | Ion Biosciences |
Type: | Calcium Indicator |
Alias: | ION Calcium Red, ICR, IRC-1 |
Shipping Condition: | RT |
Unit(s): | 10 x 50 ug, 3 x 50 ug, 500 ug |
Description: ION Calcium Red-1. Red fluorescent calcium indicator, membrane permeable. Optimal for multiplexing and tissue imaging. Excitation: 580 nm | Emission: 660 nm | Kd: 480 nM | Purity: >95% ION Calcium Red - 1 (ICR-1) is a red fluorescent (Ex/Em 580nm/660nm) calcium (Ca²⁺) indicator for intracellular Ca²⁺ measurements. ICR-1's long-wavelength emission and a large Stokes shift reduces contributions of autofluorescence, making ICR-1 AM optimal for cellular and tissue imaging applications. ICR-1 can also be multiplexed with GFP-labeled cells or other green fluorophores commonly used in experiments. Unlike some other red fluorescent Ca²⁺ indicators, ICR-1 does not accumulate in the mitochondria. Data supporting fluorescence lifetime imaging and multiphoton imaging capabilities have also been demonstrated.