Description: Formin-like protein 2/FHOD1 (formin homology 2 domain containing 1) acts as a capping and bundling protein. In cells, active FHOD1 stimulates the formation of ventral stress fibers. FHOD1 is mainly located at the intercalated disc, the special type of cell-cell contact between cardiomyocytes (25125170).FHOD1 promotes the formation of short actin filaments and transiently associates with transverse arcs, thus providing tight temporal and spatial control of the formation and turnover of transverse arcs into mature ventral stress fibers during dynamic cell behavior (24481812).
Additional Text
Gene Name
FMNL2
Uniprot ID
Q96PY5
Gene ID
114793
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 2-4 µg/ml
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.