Description: Twistnb is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. This protein contains 2 potential nuclear localization signals in the C terminus and shares 72% sequence identity with the mouse orthologs. Twistnb has highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Additional Text
Uniprot ID
Q3B726
Gene ID
221830
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
Gene Name
POLR1F
Storage Note
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.