Polyclonal Antibody to MEIS1
Catalogue Number: 11-12008-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | MEIS1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant MEIS1 protein (amino acids 163-352) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.
Additional Text
Gene ID
4211
Gene Name
MEIS1
Uniprot ID
O00470
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
Storage Note
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
11-12008 Datasheet
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