Polyclonal Antibody to HMGB3

Catalogue Number: 11-12011-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:HMGB3||HMG2A||HMG4
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Full length recombinant HMGB3 protein was used as the immunogen for this antibody.
Application: WB

Description

Description: HMGB3 (High Mobility Group-Box 3) belongs to the high mobility group box (HMG-box) subfamily. It has 99% homology with HMGB1 and HMGB2. This subfamily has a HMG-box, so it can regulate gene transcription by participating with formation of enhancesomes. The HMG-box subfamily also plays an important role in DNA replication, transcription, recombination and repair, etc. HMGB3 has been reported to have high expression in embryos and weak expression in adult tissues. HMGB3 is important in keeping the balance between self-renewal and differentiation status in mouse hematopoietic stem cells.

Additional Text

Gene Name

HMGB3

Uniprot ID

O15347

Gene ID

3149

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 2-4 µg/ml

Storage Note

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.