Polyclonal Antibody to SPZ1/TSP1
Catalogue Number: 11-12019-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | SPZ1||TSP1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant SPZ1/TSP1 protein (amino acids 10-213) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: Spz1, a bHLH-zip protein, acts as a proto-oncogene regulated by a MAPK signaling pathway that can increase cell proliferation and tumorigenic activity as well as leading to primary tumor formation (15899793). It is expressed specifically in the testis and epididymis (11165476). Spz1 is a specific binding partner of the gamma2 catalytic subunit of Phosphatase-1c-gamma (PP1c-gamma). The interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males.
Additional Text
Gene Name
SPZ1
Gene ID
84654
Uniprot ID
Q9BXG8
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 1-2 µg/ml
Storage Note
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
11-12019 Datasheet
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