Polyclonal Antibody to DPPA4

Catalogue Number: 11-12042-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:DPPA4
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant DPPA4 protein (amino acids 1-206) was used as the immunogen for this antibody.
Application: WB

Description

Description: DPPA4 (Developmental pluripotency-associated 4) is a DNA binding SAP domain-containing protein. It is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. It is also mutated in some cancers. DPPA4 overexpression induces cell proliferation through genes related to regulation of G1/S transition. DPPA4 Contains a functional HMG/POU cassette and behaves as a Sox2:Oct-3/4 target gene. Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis.

Additional Text

Gene Name

DPPA4

Gene ID

55211

Purification

Protein A purified

Uniprot ID

Q7L190

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 1-2 µg/ml

Storage Note

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.