Description: Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.
Additional Text
Gene Name
UNC93B1
Uniprot ID
Q9H1C4
Gene ID
81622
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 4-6 µg/ml
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.