Description: CACTIN is a conserved protein, discovered as a novel interactor of Drosophila IkappaB protein Cactus. It is highly conserved during evolution and plays a key role in early embryonic development. It is characterized as a negative regulator of many different developmental processes, but only found to play an immune role in humans. CACTIN localizes to nuclear speckles and colocalizes with known splicing proteins. It binds to a putative component of the spliceosome, major role for CACTIN in splicing.
Additional Text
Gene ID
58509
Gene Name
CACTIN
Uniprot ID
Q8WUQ7
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 2-4 µg/ml
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.