Polyclonal Antibody to TLR1

Catalogue Number: 11-3041-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:TLR1||KIAA0012
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody.
Application: WB

Description

Description: Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family, which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers, but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus, and small intestine.

Additional Text

Gene Name

TLR1

Gene ID

7096

Uniprot ID

Q15399

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 4-6 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.