Polyclonal Antibody to p65
Catalogue Number: 11-6002-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | RELA||NFKB3 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A partial length recombinant p65 protein (amino acids 1-200) was used as the immunogen for this antibody. |
| Application: | WB |
Description
Description: P65 is a subunit of the NF-KappaB, a second messenger, which activates the transcription of a number of genes in multiple tissues. It is a ubiquitously expressed protein that can bind to the kB site alone. In addition, p65 is shown to be the subunit responsible for providing transcriptional activity of the NF-kB (p65-p50) heterodimeric complex. The inhibitory effect of I-KappaB upon NF-KappaB in the cytoplasm is exerted primarily through the interaction with P65. It shows a weak DNA binding site, which could contribute directly to DNA binding in the NF-KappaB complex.
Additional Text
Gene Name
RELA
Gene ID
5970
Uniprot ID
Q04206
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 2-4 µg/ml
Storage Note
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
11-6002 Datasheet
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