Polyclonal Antibody to CUEDC2

Catalogue Number: 11-6003-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:CUEDC2||C10orf66||HOYS6
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.
Application: WB

Description

Description: CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.

Additional Text

Gene Name

CUEDC2

Gene ID

79004

Purification

Protein A purified

Uniprot ID

Q9H467

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 1-2 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.