Description: LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.
Additional Text
Gene Name
KDM1A
Uniprot ID
O60341
Gene ID
23028
Purification
Protein A purified
Antibody Clonality
Polyclonal
Application Notes
Western blot analysis: 0.5-2.0 µg/ml, Immunohistochemical analysis: 5 µg/ml
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.