Polyclonal Antibody to LSD1

Catalogue Number: 11-7004-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:KDM1A||AOF2||KDM1||KIAA0601||LSD1
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A partial length recombinant LSD1 protein (amino acids 97-328) was used as the immunogen for this antibody.
Application: WB, IHC

Description

Description: LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.

Additional Text

Gene Name

KDM1A

Uniprot ID

O60341

Gene ID

23028

Purification

Protein A purified

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 0.5-2.0 µg/ml, Immunohistochemical analysis: 5 µg/ml

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.