Polyclonal Antibody to Histone H3.3

Catalogue Number: 11-7007-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:H3F3A||H3.3A||H3F3||PP781
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Full length recombinant Histone H3.3 protein was used as the immunogen for this antibody.
Application: WB, IHC

Description

Description: Histones are major chromatin proteins involved in nucleosome assembly. Their major function is to compact long DNA strands inside the nucleus and chromatin regulation. Histone H3.3 is a replication independent variant of Histone H3 which is generally expressed in quiescent or terminally differentiated cells. Modifications in Histone H3.3 are associated with transcriptional activation and acts as an epigenetic mark of transcriptionally active chromatin. Histone H3.3 is a 15 kDa protein which is expressed throughout the cell cycle independently of DNA synthesis in all eukaryotic genomes.

Additional Text

Uniprot ID

P84243

Purification

Protein A purified

Gene ID

3020; 3021

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 1-2 µg/ml, Immunohistochemical analysis: 5 µg/ml

Gene Name

H3-3A, H3-3B

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.