Polyclonal Antibody to Histone H2A

Catalogue Number: 11-7017-ABO

Manufacturer:	Abeomics
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	HIST1H2AB\|\|H2AFM
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	100 ug, 25 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Full length recombinant Histone H2A protein was used as the immunogen for this antibody.
Application:	WB, IHC

Overview
Datasheets

Description

Description: Histone H2A is one of the five main histone proteins that is approximately 14 kDa protein consisting of 130 amino acid residues and present in the nucleosome in the form of H2A-H2B heterodimer. H2A is mainly composed of non-allelic variants and interestingly atypical variants, such as, MacroH2As, H2A.X, H2A-Bbd, differ considerably in size with H2A. H2A undergoes various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination, which occur in response to various stimuli and directly affect the accessibility of chromatin to transcription factors. This gene is mainly expressed on blood, brain, breast and it plays a significant role in the disease, riddle syndrome.

Additional Text

Uniprot ID

P04908

Purification

Protein A purified

Gene ID

3012; 8335

Antibody Clonality

Polyclonal

Application Notes

Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml

Gene Name

H2AC4, H2AC8

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

11-7017 Datasheet

Price

£242.00

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