Recombinant Mouse Monoclonal Antibody to CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker)(Clone : rKi-1/779)

Catalogue Number: 12-1013-ABO

Manufacturer:	Abeomics
Type:	Recombinant Monoclonal
Alias:	CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:
Clone:	rKi-1/779
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human TNFRSF8 protein
Application:	IHC

Overview
Datasheets

Description

Description: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Additional Text

Gene ID

943

Gene Name

TNFRSF8

Uniprot ID

P28908

Purification

Purified

Antibody Clonality

Monoclonal

Application Notes

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Storage Note

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

12-1013 Datasheet

Price

£533.00

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