Anti-Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) Recombinant Mouse Monoclonal Antibody (Clone:rCALD1/820)

Catalogue Number: 12-1085-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	CAD; CALD1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; CDM; HCAD; LCAD; NAG22
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rCALD1/820
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human CALD1 protein
Application:	WB, IHC

Overview
Datasheets

Description

Description: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Additional Text

Gene Name

CALD1

Gene ID

800

Uniprot ID

Q05682

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

Western Blot (1-2µg/ml); ,Immunohistology (Formalin-fixed) (0.25-0.5µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)

Storage Note

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

12-1085 Datasheet

Price

£533.00

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