Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Recombinant Mouse Monoclonal Antibody (Clone:rLPFS2/1611)

Catalogue Number: 12-1104-ABO

Manufacturer:Abeomics
Shelf Life:24 months
Type:Recombinant Monoclonal
Alias:LPFS2; S152; T cell activation antigen S152; T-cell activation antigen CD27; T14; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Host name: Mouse
Clone: rLPFS2/1611
Isotype: IgG1, kappa
Immunogen: Recombinant human CD22 protein fragment (around aa 52-178) (exact sequence is proprietary)
Application: FACS, IHC

Description

Description: Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Additional Text

Uniprot ID

P26842

Gene Name

CD27

Purification

Protein A/G Purified

Gene ID

939

Antibody Clonality

Monoclonal

Application Notes

Flow Cytometry (1-2µg/million cells);,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Storage Note

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.