Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Recombinant Mouse Monoclonal Antibody (Clone:rLPFS2/1611)
Catalogue Number: 12-1104-ABO
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | LPFS2; S152; T cell activation antigen S152; T-cell activation antigen CD27; T14; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rLPFS2/1611 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant human CD22 protein fragment (around aa 52-178) (exact sequence is proprietary) |
| Application: | FACS, IHC |
Description
Description: Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
Additional Text
Uniprot ID
P26842
Gene Name
CD27
Purification
Protein A/G Purified
Gene ID
939
Antibody Clonality
Monoclonal
Application Notes
Flow Cytometry (1-2µg/million cells);,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Storage Note
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
12-1104 Datasheet
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