Anti-CD44v4 (Marker of Tumor Metastasis) Recombinant Mouse Monoclonal Antibody (Clone:rCD44v4/1219)
Catalogue Number: 12-1117-ABO
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Figure 1: Formalin-fixed, paraffin-embedded human Bladder stained with CD44v4 Mouse Recombinant Monoclonal Antibody (rCD44v4/1219).
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Figure 2: Formalin-fixed, paraffin-embedded human Cervical Squamous Cell Carcinoma stained with CD44v4 Mouse Recombinant Monoclonal Antibody (rCD44v4/1219).
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Figure 3:SDS-PAGE Analysis Purified CD44v4 Mouse Recombinant Monoclonal Antibody (rCD44v4/1219).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rCD44v4/1219 |
| Isotype: | IgG2a, kappa |
| Immunogen: | Recombinant fragment corresponding to the v4 domain of human CD44 |
| Application: | IHC |
Description
Description: This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44.The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Additional Text
Gene Name
CD44
Gene ID
960
Uniprot ID
P16070
Purification
Protein A/G Purified
Specificity
LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8); Epican; Extracellular Matrix Receptor III (ECM III); GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blo
Antibody Clonality
Monoclonal
Application Notes
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Storage Note
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
12-1117 Datasheet
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