Catalogue Number: 12-1155-ABO
Manufacturer: | Abeomics |
Shelf Life: | 24 months |
Type: | Recombinant Monoclonal |
Alias: | CK16; Cytokeratin-16; Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK); K1CP; Keratin Type I Cytoskeletal 16; Keratin-16; KRT16A |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 20 ug |
Host name: | Mouse |
Clone: | KRT16/1714 |
Isotype: | IgG1, kappa |
Immunogen: | Recombinant full-length human KRT16 protein |
Application: | IHC |
Description: Cytokeratins are a family of intermediate filament proteins that assemble into filaments throµgh forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.
3868
KRT16
P08779
Protein A/G Purified
Monoclonal
Immunohistochemistry (Formalin-fixed) (0.1-0.2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.