Catalogue Number: 12-1157-ABO
Manufacturer: | Abeomics |
Shelf Life: | 24 months |
Type: | Recombinant Monoclonal |
Alias: | k19; k1cs; Keratin 19 Keratin Type i 40kD; krt19 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 20 ug |
Host name: | Mouse |
Clone: | rKRT19/799 |
Isotype: | IgG1, kappa |
Immunogen: | Recombinant full-length human KRT19 protein |
Application: | FACS, IF, WB, IHC |
Description: This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, althoµgh 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
KRT19
3880
P08727
Protein A/G Purified
Monoclonal
Flow Cytometry (1-2µg/million cells); Immunofluorescence (1-2µg/ml); Western Blot (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.