Anti-Cytokeratin 8/18 Recombinant Mouse Monoclonal Antibody (Clone:rKRT8.18/1346)
Catalogue Number: 12-1162-ABO
12-1162 Image
12-1162 Image
12-1162 Image
Figure 1: Formalin-fixed, paraffin-embedded Human colon stained with Cytokeratin 8/18 Mouse Recombinant Monoclonal Antibody (rKRT8.18/1346).
12-1162 Image
Figure 2: SDS-PAGE Analysis Purified Cytokeratin 8/18 Mouse Monoclonal Antibody (rKRT8.18/1346).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein; CK18; CYK18 Cytokeratin Endo B; K18; Keratin-18; Kerd; KRT18 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rKRT8.18/1346 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant full-length human KRT8 protein and recombinant full-length human KRT18 protein |
| Application: | IHC |
Description
Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Additional Text
Purification
Protein A/G Purified
Uniprot ID
P05783, P05787
Antibody Clonality
Monoclonal
Gene ID
3856; 3875
Application Notes
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Gene Name
KRT18, KRT8
Storage Note
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
12-1162 Datasheet
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