Anti-Estrogen Receptor, alpha (Marker of Estrogen Dependence) Recombinant Mouse Monoclonal Antibody (Clone:rESR1/1935)

Catalogue Number: 12-1177-ABO

Manufacturer:Abeomics
Shelf Life:24 months
Type:Recombinant Monoclonal
Alias:Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 +49 isoform; Nuclear receptor subfamily 3 group A member 1
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Host name: Mouse
Clone: rESR1/1935
Isotype: IgG1, kappa
Immunogen: Recombinant full-length human Estrogen Receptor alpha protein
Application: WB, IHC

Description

Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

Additional Text

Gene ID

2099

Gene Name

ESR1

Uniprot ID

P03372

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

Western Blot (1-2µg/ml);,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Storage Note

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.