Anti-Kappa Light Chain (B-Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:rL1C1)

Catalogue Number: 12-1203-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rL1C1
Isotype:	IgG1, kappa
Immunogen:	Human B-Lymphoma Cells
Application:	IHC

Overview
Datasheets

Description

Description: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Additional Text

Purification

Protein A/G Purified

Gene Name

IGKC

Gene ID

3514

Antibody Clonality

Monoclonal

Uniprot ID

P01601, P01834

Application Notes

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Storage Note

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

12-1203 Datasheet

Price

£533.00

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