Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Recombinant Mouse Monoclonal Antibody (Clone:rCDH16/1071)
Catalogue Number: 12-1207-ABO
12-1207 Image
12-1207 Image
12-1207 Image
Figure 1: Formalin-fixed, paraffin-embedded Human Renal Cell Carcinoma stained with KSP-Cadherin Mouse Recombinant Monoclonal Antibody (rCDH16/1071).
12-1207 Image
Figure 2: SDS-PAGE Analysis of Purified KSP-Cadherin Mouse Recombinant Monoclonal Antibody (rCDH16/1071).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | Cadherin-16 (CDH16); Kidney-specific cadherin; Ksp-cadherin antibody |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rCDH16/1071 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant full-length human CDH16 protein |
| Application: | FACS, WB, IHC |
Description
Description: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is sµggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been sµggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Additional Text
Gene Name
CDH16
Gene ID
1014
Uniprot ID
O75309
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Flow Cytometry (1-2µg/million cells); Western Blot (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Storage Note
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
12-1207 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations