Catalogue Number: 12-1209-ABO
Manufacturer: | Abeomics |
Shelf Life: | 24 months |
Type: | Recombinant Monoclonal |
Alias: | Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 20 ug |
Host name: | Mouse |
Clone: | rMLANA/1905 |
Isotype: | |
Immunogen: | Recombinant full-length human MART-1 protein |
Description: This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
2315
MLANA
Q16655
Protein A/G Purified
Monoclonal
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.