Anti-Napsin A (Lung Adenocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (Clone:rNAPSA/1239)

Catalogue Number: 12-1221-ABO

Manufacturer:Abeomics
Shelf Life:24 months
Type:Recombinant Monoclonal
Alias:ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Host name: Mouse
Clone: rNAPSA/1239
Isotype: IgG1, kappa
Immunogen: Recombinant fragment of human Napsin-A protein (aa 189-299) (exact sequence is proprietary)
Application: IHC

Description

Description: Napsin is a pepsin-like aspartic proteinaseconnected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Additional Text

Purification

Protein A/G Purified

Gene ID

9476

Gene Name

NAPSA

Uniprot ID

O96009

Antibody Clonality

Monoclonal

Application Notes

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Storage Note

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.