Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rVWF/1465)
Catalogue Number: 12-1265-ABO
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Figure 1: Formalin-fixed, paraffin-embedded human Tonsil stained with vWF Mouse Recombinant Monoclonal Antibody (rVWF/1465).
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Figure 2: Western Blot Analysis A) Recombinant Protein (B) human lung lysate vWF Mouse Recombinant Monoclonal Antibody (rVWF/1465).
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Figure 3:SDS-PAGE Analysis Purified vWF Mouse Recombinant Monoclonal Antibody (rVWF/1465).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD) |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rVWF/1465 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant fragment of human vWF protein (aa 1815-1939) (exact sequence is proprietary) |
| Application: | IP, WB, IHC |
Description
Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers althoµgh not all tumors of endothelial differentiation contain this antigen.
Additional Text
Gene Name
VWF
Purification
Protein A/G Purified
Gene ID
7450
Uniprot ID
P04275
Antibody Clonality
Monoclonal
Application Notes
Western Blot (1-2µg/ml); Immunoprecipitation (0.5-1ug/500ug protein lysate);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Storage Note
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
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