NCOA3/SRC3 CUTANA™ CUT&RUN Antibody
Catalogue Number: 13-2013-EPC
| Manufacturer: | EpiCypher |
| Shelf Life: | 12 months |
| Preservative: | 0.09% sodium azide |
| Ph: | 7-8 |
| Physical state: | Aff. Pur. IgG |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Host Cell: | Rabbit|Antibody |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | A synthetic peptide corresponding to human NCOA3/SRC3 amino acids 900 - 950. |
| Application: | WB, CUT&RUN |
Description
Description: This antibody meets EpiCypher's "CUTANA Compatible" criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated CUTANA approach using EpiCypher optimized protocols (EpiCypher.com/resources/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. Consistent with its role as a nuclear receptor coactivator that facilitates ER-mediated transcription (1), NCOA3 (SRC3) antibody shows CUT&RUN peaks in response to estradiol stimulation (Figure 1) that overlap with known estrogen response element (ERE) binding motifs (Figure 2). SRC3 CUT&RUN peaks also overlap with ER alpha antibodies (N- and C-term) (Figure 2).
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Application Notes
Recommended Dilutions: CUT&RUN: 0.5 µg WB: 1:2,000 - 1:10,000
Storage Note
Stable for 1 year at 4°C from date of receipt.
13-2013 Datasheet
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