FITC-C6-D(OMe)E(OMe)VD(OMe)-FMK

Catalogue Number: 13417-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Probes
Shipping Condition:RT
Unit(s): 100 ug

Description

Description: Activation of caspases plays a central role in apoptosis. FITC-C6-D(OMe)E(OMe)VD(OMe)-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. FITC-C6-D(OMe)E(OMe)VD(OMe)-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells. Based on our in-house studies FITC-C6-D(OMe)E(OMe)VD(OMe)-FMK gave the highest signal/background ratio compared to other DEVD-FMK probes we tested. The FITC label allows for direct detection of activated caspases in apoptotic cells by fluorescence microscopy, flow cytometry, or fluorescence plate reader.

Additional Text

Storage Note

Freeze (< -15 °C); Minimize light exposure;|12 months