(Ac-IETD)2-R110
Catalogue Number: 13431-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Enzyme Substrates |
| Shipping Condition: | RT |
| Unit(s): | 1 mg |
Description
Description: Since highly purified rhodamine 110 (R110)-derived substrates are locked in the lactone configuration they are colorless and non-fluorescent. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments. R110-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. This R110 substrate is specific for caspase 8. Our R110-based substrates are highly purified to eliminate the trace amount of free R110 that is not detectable by HPLC, but causes significant assay background.
Additional Text
Storage Note
Freeze (< -15 °C); Minimize light exposure;|12 months
13431 MSDS
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