AF9 YEATS Domain, Recombinant Human

Catalogue Number: 15-0071-EPC

Manufacturer:EpiCypher
Shelf Life:6 months
Type:DNA Binding Proteins
Host Cell:E.coli
Shipping Condition:Dry Ice
Unit(s): 100 ug
Host name: Human
Clone:
Isotype:
Immunogen:

Description

Description: The AF9 protein is part of the super elongation complex and also associates with the histone methyltransferase DOT1L [1]. Translocation of the AF9 gene to the MLL gene, resulting in an MLL/AF9 fusion, is the most common chromosomal rearrangement involving MLL in de novo AML [2].

Additional Text

Protein Tag

6xHIS Tag

Application Notes

AF9 YEATS Domain is useful for protein binding and screening experiments examining crotonylated and acetylated protein substrates.

Storage Note

Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.